Invitrogen™ TIAL1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA596501

Catalog No. PIPA596501

Description

Immunogen sequence: EGHVVKCYWG KESPDMTKNF QQVDYSQWGQ WSQVYGNPQQ YGQYMANGWQ VPPYGVYGQP WNQQGFGVDQ SPSAAWMGGF GAQPPQGQAP PPVIPPPNQA GYGMASYQTQ; Positive Samples: A-549, HeLa, K-562; Cellular Location: Cytoplasm, Cytoplasmic granule, Nucleus.

The protein encoded by this gene is a member of a family of RNA-binding proteins, has three RNA recognition motifs (RRMs), and binds adenine and uridine-rich elements in mRNA and pre-mRNAs of a wide range of genes. It regulates various activities including translational control, splicing and apoptosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The different isoforms have been show to function differently with respect to post-transcriptional silencing.

Specifications

• Antigen: TIAL1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TIAL1
• Gene Alias: 5330433G13Rik; aging-associated gene 7 protein; AL033329; mTIAR; Nucleolysin TIAR; RNA binding protein TIAR (TIA-1 related); TCBP; T-cluster binding protein; Tia1 cytotoxic granule-associated RNA binding protein-like 1; TIA-1-related nucleolysin; TIA-1-related protein; Tial 1 cytotoxic granule-associated RNA- binding protein-like 1; TIAL1; Tial1 cytotoxic granule-associated RNA binding protein-like 1; Tial1 cytotoxic granule-associated RNA-binding protein-like 1; TIAR
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21843, 361655, 7073
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
• Concentration: 0.73 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: P70318, Q01085
• Gene Symbols: TIAL1
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 266-375 of human TIAL1 (NP_0032431).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov