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Invitrogen™ TIAM2 Polyclonal Antibody
Rabbit Polyclonal Antibody
Supplier: Invitrogen™ PA548604
Description
TIAM2 Polyclonal Antibody for Western Blot
Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane. Activates specifically RAC1, but not CDC42 and RHOA.
Specifications
TIAM2 | |
Polyclonal | |
PBS with 0.09% sodium azide; pH 7.4 | |
Q6ZPF3, Q8IVF5 | |
Tiam2 | |
KLH conjugated synthetic peptide between 357-385 amino acids of human TIAM2. | |
400 μL | |
Primary | |
Human, Mouse | |
Antibody | |
IgG |
Western Blot | |
Unconjugated | |
Tiam2 | |
3000002F19Rik; KIAA2016; mKIAA2016; RAS-related C3 botulinum substrate 1, guanine nucleotide exchange factor 1; SIF and TIAM1-like exchange factor; Stef; T cell lymphoma invasion and metastasis 2; T-cell lymphoma invasion and metastasis 2; T-cell lymphoma invasion and metastasis 2; RAS-related C3 botulinum substrate 1, guanine nucleotide exchange factor 1; TIAM2; TIAM-2; T-lymphoma invasion and metastasis-inducing protein 2 | |
Rabbit | |
Antigen affinity chromatography, Protein A | |
RUO | |
24001, 26230 | |
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
Liquid |
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