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Invitrogen™ TIAM2 Polyclonal Antibody
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Catalog No. PIPA5142639
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100 μg
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Catalog No. Quantity
PIPA5142639 100 μg
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Catalog No. PIPA5142639 Supplier Invitrogen™ Supplier No. PA5142639
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Description

Goat Polyclonal Antibody

Additional Information: This antibody is expected to recognize isoform a (NP_036586.2) only. This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane. Activates specifically RAC1, but not CDC42 and RHOA.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TIAM2
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Tiam2
Gene Accession No. Q8IVF5
Gene Alias 3000002F19Rik; KIAA2016; mKIAA2016; RAS-related C3 botulinum substrate 1, guanine nucleotide exchange factor 1; SIF and TIAM1-like exchange factor; Stef; T cell lymphoma invasion and metastasis 2; T-cell lymphoma invasion and metastasis 2; T-cell lymphoma invasion and metastasis 2; RAS-related C3 botulinum substrate 1, guanine nucleotide exchange factor 1; TIAM2; TIAM-2; T-lymphoma invasion and metastasis-inducing protein 2
Gene Symbols Tiam2
Host Species Goat
Immunogen Peptide with sequence TLQGSKNHSNT-C (aa 9-19).
Purification Method Ammonium sulfate precipitation
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 26230
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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