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Invitrogen™ TICAM2 Polyclonal Antibody
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Catalog No. PIPA529576
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100 μL
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PIPA529576 100 μL
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Catalog No. PIPA529576 Supplier Invitrogen™ Supplier No. PA529576
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Description

Rabbit Polyclonal Antibody

Recommended positive controls: HCT116. Predicted reactivity: Pig (82%), Rhesus Monkey (97%), Chimpanzee (99%), Bovine (80%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

TRAM, or TRIF-related adaptor molecule (TICAM2), plays an essential role in the MyD88-independent signaling of TLR4. The functional absence of TRAM in vascular endothelial cells restricts TLR4 signaling to MyD88-dependent pathway. Overexpression of TRAM cDNA in endothelial cells reconstituted LPS-induced Trif-dependent NF-kB activation and cxcl10 promoter activity.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TICAM2
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry
Classification Polyclonal
Concentration 0.72 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7
Gene TICAM2
Gene Accession No. Q86XR7
Gene Alias B430113A10; cytoplasmic adaptor; MyD88-4; NF-kappa-B-activating protein 502; putative NF-kappa-B-activating protein 502; TAG; TICAM2; TICAM-2; TIR domain-containing adapter molecule 2; TIR domain-containing adapter protein; TIRAP3; Tirp; toll like receptor adaptor molecule 2; toll/interleukin-1 receptor (TIR) domain-containing adapter protein; toll/interleukin-1 receptor domain-containing protein; Toll-interleukin I receptor domain (TIR)-containing adaptor molecule (TICAM) 2; toll-like receptor adaptor molecule 2; toll-like receptor adaptor protein 3; Tram; Trif; TRIF-related adapter molecule; TRIF-related adapter molecule TRAM; TRIF-related adaptor molecule
Gene Symbols TICAM2
Host Species Rabbit
Immunogen Full length human TICAM2 Recombinant protein.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 353376
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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