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TIGIT Mouse anti-Human, Clone: 20A9, GenScript™

Catalog No. 502120702
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40 μg
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Catalog No. Quantity
50-212-0702 40 μg
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Catalog No. 50-212-0702 Supplier Genscript Corporation Supplier No. A0198140
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Description

Mouse Monoclonal Antibody

Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/mL. T cell immunoreceptor with Ig and ITIM domains (TIGIT), also known as VSTM3, is a type I transmembrane protein, which belongs to the PVR family of immunoglobulin-like domain containing proteins. It is composed of an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on activated T cells, follicular T helper, memory T cells, and regulatory T cells and NK cells. TIGIT binds to CD155 (PVR) with high affinity and it regulates T-cell mediated immunity via the CD226/TIGIT-PVR pathway. TIGIT also serves as a negative regulator of NK and T cell activation.

Human TIGIT Antibody (20A9), mAb, Mouse is produced from a hybridoma resulting from the fusion of partner and B-lymphocytes obtained from a mouse immunized with TIGIT.

TIGIT Monoclonal antibody specifically detects TIGIT in Human samples. It is validated for ELISA, Flow Cytometry

Specifications

Antigen TIGIT
Applications ELISA, Flow Cytometry
Classification Monoclonal
Clone 20A9
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide; pH 7.4
Gene TIGIT
Gene Accession No. Q495A1
Gene Alias ENSMUSG00000071552; T cell immunoreceptor with Ig and ITIM domains; T-cell immunoreceptor with Ig and ITIM domains; TIGIT; V-set and immunoglobulin domain containing 9; V-set and immunoglobulin domain-containing protein 9; V-set and transmembrane domain containing 3; V-set and transmembrane domain-containing protein 3; VSIG9; VSTM3; Washington University cell adhesion molecule; WUCAM
Host Species Mouse
Immunogen Recombinant TIGIT protein
Purification Method Protein A
Quantity 40 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 201633
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Lyophilized
Isotype IgG1
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