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Invitrogen™ TIM-4 Monoclonal Antibody (2A1H5)
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Catalog No. FERMA548798
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100 μg
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Catalog No. Quantity
FERMA548798 100 μg
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Catalog No. FERMA548798 Supplier Invitrogen™ Supplier No. MA548798
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Description

Mouse Monoclonal Antibody

TIM-4 Monoclonal Antibody for Western Blot, ICC/IF, Flow, ELISA

The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.
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Specifications

Antigen TIM-4
Applications ELISA, Flow Cytometry, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 2A1H5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.05% sodium azide
Gene TIMD4
Gene Accession No. Q96H15
Gene Alias B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4
Gene Symbols TIMD4
Host Species Mouse
Immunogen Purified recombinant fragment of human TIMD4 (AA: extra 25-314) expressed in E. Coli.
Purification Method Protein G
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 91937
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG1
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