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Invitrogen™ TIMD4 Polyclonal Antibody
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Catalog No. PIPA520247
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100 μg
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Catalog No. Quantity
PIPA520247 100 μg
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Catalog No. PIPA520247 Supplier Invitrogen™ Supplier No. PA520247
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Description

Rabbit Polyclonal Antibody

A suggested positive control is Jurkat cell lysate. PA5-20247 can be used with blocking peptide PEP-0365.

The T cell immunoglobulin and mucin domain containing protein (TIM) family encodes cell surface receptors that are involved in the regulation of T helper (Th) -1 and -2 cell-mediated immunity. TIM-4, which is preferentially expressed on macrophages and dendritic cells, is the natural ligand of TIM-1, and this binding leads to T-cell expansion and cytokine production. Unlike other members of the TIM family, TIM-4 lacks a putative tyrosine phosphorylation signal sequence in its intracellular domain. The TIM-4 gene maps to a locus associated with predisposition to asthma in both mice and humans and with its connection to TIM-1-triggered Th2 responsiveness, may be considered as a candidate disease/predisposition gene for asthma.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TIMD4
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.02% sodium azide
Gene TIMD4
Gene Accession No. Q6U7R4, Q96H15
Gene Alias B430010N18Rik; RGD1564516; smuckler; soluble TIM 4; Spleen, mucin-containing, knockout of lymphotoxin protein; sTIM 4; T cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain containing 4; T-cell immunoglobulin and mucin domain-containing protein 4; T-cell immunoglobulin mucin receptor 4; T-cell membrane protein 4; Tim4; TIM-4; TIMD4; TIMD-4
Gene Symbols TIMD4
Host Species Rabbit
Immunogen A 15 amino acid peptide from near the carboxy terminus of human TIM-4.
Purification Method Antigen affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 276891, 497891, 91937
Target Species Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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