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TIMELESS Rabbit anti-Human, Polyclonal, Proteintech
SDP

Catalog No. 501729439 Shop All Proteintech Group Inc Products
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50-172-9439 150 μL
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Catalog No. 50-172-9439 Supplier Proteintech Group Inc Supplier No. 144211AP150UL
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Description

Rabbit Polyclonal Antibody

Timeless is required for normal progression of S-phase. Involved in the circadian rhythm autoregulatory loop. Negatively regulates CLOCK-NPAS2/BMAL1-induced transactivation of PER1 possibly via translocation of PER1 into the nucleus. Promotes TIPIN nuclear localization. Involved in cell survival after DNA damage or replication stress. May be specifically required for the ATR-CHK1 pathway in the replication checkpoint induced by hydroxyurea or ultraviolet light. May also play an important role in epithelial cell morphogenesis and formation of branching tubules.

Specifications

Antigen TIMELESS
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.23 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TIMELESS
Gene Accession No. Q9UNS1
Gene Alias hTIM, Protein timeless homolog, TIM, TIM1, TIMELESS, timeless homolog (Drosophila), TIMELESS1
Gene Symbols TIMELESS
Host Species Rabbit
Immunogen TIMELESS Fusion Protein Ag5767
Purification Method Antigen Affinity Chromatography
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 8914
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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