Invitrogen™ TIMM44 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5120549

Catalog No. PIPA5120549

Description

Positive test controls include: U-87MG, K562, mouse liver, rat kidney. Immunogen sequence: AKTAKQSAES VSKGGEKLGR TAAFRALSQG VESVKKEIDD SVLGQTGPYR RPQRLRKRTE FAGDKFKEEK VFEPNEEALG VVLHKDSKWY QQWKDFKENN VVFNRFFEMK MKYDESDNAF IRASRALTDK VTDLLGGLFS KTEMSEVLTE ILRVDPAFDK DRFLKQCEND IIPNVLEAMI SGELDILKDW CYEATYSQLA HPIQQAKALG LQFHSRILDI DNVDLAMGKM MEQGPVLIIT FQAQLVMVVR NPKGEVVEGD PDKVLRMLYV WALCRDQDEL NPYAAWRLLD ISASSTEQIL.

This gene encodes a peripheral membrane protein associated with the mitochondrial inner membrane translocase, which functions in the import of proteins across the mitochondrial inner membrane and into the mitochondrial matrix. The encoded protein mediates binding of mitochondrial heat shock protein 70 to the translocase of inner mitochondrial membrane 23 (TIM23) complex. Expression of this gene is upregulated in kidney in a mouse model of diabetes. A mutation in this gene is associated with familial oncocytic thyroid carcinoma.

Specifications

• Antigen: TIMM44
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TIMM44
• Gene Alias: 0710005E20Rik; D8Ertd118e; Mimt44; Mitochondrial import inner membrane translocase subunit TIM44; Tim44; TIMM44; translocase of inner mitochondrial membrane 44; translocase of inner mitochondrial membrane 44 homolog; translocase of inner mitochondrial membrane 44 homolog (yeast); translocator of inner mitochondrial membrane 44; translocator of inner mitochondrial membrane 44; DNA segment, Chr 8, ERATO Doi 118, expressed
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 10469, 21856, 29635
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot, Immunocytochemistry
• Concentration: 2.22 mg/mL
• Formulation: PBS with 50% glycerol and 0.01% thimerosal; pH 7.3
• Gene Accession No.: O35094, O35857, O43615
• Gene Symbols: TIMM44
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 153-452 of human TIMM44 (NP_006342.2).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG