Invitrogen™ TIMM50 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA546303

Catalog No. PIPA546303

Description

Peptide sequence: EDDPLAAFKQ RQSRLEQEEQ QRLAELSKSN KQNLFLGSLT SRLWPRSKQP Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 75%.

TIMM50 (Mitochondrial import inner membrane translocase subunit TIM50) is an enzyme that in humans is encoded by the TIMM50 gene. Tim50 is a subunit of the Tim23 translocase complex in the inner mitochondrial membrane. Mutations in TIMM50 can lead to epilepsy, severe intellectual disability, and 3-methylglutaconic aciduria. TIMM50 expression is increased in breast cancer cells and decreased in hypertrophic hearts.

Specifications

• Antigen: TIMM50
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TIMM50
• Gene Alias: 2810403L02Rik; AU015082; homolog of yeast Tim50; hypothetical protein LOC505489; LOC687295; LOW QUALITY PROTEIN: mitochondrial import inner membrane translocase subunit TIM50; MGC102733; mitochondrial import inner membrane translocase subunit TIM50; PRO1512; similar to translocase of inner mitochondrial membrane 50 homolog; TIM50; TIM50L; Tim50-like protein; timm50; timm50 protein; translocase of inner mitochondrial membrane 50; translocase of inner mitochondrial membrane 50 homolog; translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae); translocase of inner mitochondrial membrane 50-like protein; zgc:66357
• Host Species: Rabbit
• Purification Method: Affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 92609
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: Western Blot
• Concentration: 0.5 mg/mL
• Formulation: PBS with 2% sucrose and 0.09% sodium azide
• Gene Accession No.: Q3ZCQ8
• Gene Symbols: TIMM50
• Immunogen: Synthetic peptide directed towards the C-terminal of human TIMM50 (aa 304-353).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov