Invitrogen™ TIMM50 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5110489

Catalog No. PIPA5110489

Description

Immunogen sequence: GNNPVDENGA KIPDEFDNDP ILVQQLRRTY KYFKDYRQMI IEPTSPCLLP DPLQEPYYQP PYTLVLELTG VLLHPEWSLA TGWRFKKRPG IETLFQQLAP LYEIVIFTSE TGMTAFPLID SVDPHGFISY RLFRDATRYM DGHHVKDISC LNRDPARVVV VDCKKEAFRL QPYNGVALRP WDGNSDDRVL LDLSAFLKTI ALNGVEDVRT VLEHYALEDD PLAAFKQRQS RLEQEEQQRL AELSKSNKQN LFLGSLTSRL WPRSKQP.

TIMM50 (Mitochondrial import inner membrane translocase subunit TIM50) is an enzyme that in humans is encoded by the TIMM50 gene. Tim50 is a subunit of the Tim23 translocase complex in the inner mitochondrial membrane. Mutations in TIMM50 can lead to epilepsy, severe intellectual disability, and 3-methylglutaconic aciduria. TIMM50 expression is increased in breast cancer cells and decreased in hypertrophic hearts.

Specifications

• Antigen: TIMM50
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TIMM50
• Gene Alias: 2810403L02Rik; AU015082; homolog of yeast Tim50; hypothetical protein LOC505489; LOC687295; LOW QUALITY PROTEIN: mitochondrial import inner membrane translocase subunit TIM50; MGC102733; mitochondrial import inner membrane translocase subunit TIM50; PRO1512; similar to translocase of inner mitochondrial membrane 50 homolog; TIM50; TIM50L; Tim50-like protein; timm50; timm50 protein; translocase of inner mitochondrial membrane 50; translocase of inner mitochondrial membrane 50 homolog; translocase of inner mitochondrial membrane 50 homolog (S. cerevisiae); translocase of inner mitochondrial membrane 50-like protein; zgc:66357
• Host Species: Rabbit
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 66525, 92609
• Content And Storage: -20°C, Avoid Freeze/Thaw Cycles
• Form: Liquid

• Applications: ELISA, Western Blot
• Concentration: 0.83 mg/mL
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene Accession No.: Q3ZCQ8, Q9D880
• Gene Symbols: TIMM50
• Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 190-456 of human TIMM50 (NP_001001563.1).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov