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Invitrogen™ TIMM8A Monoclonal Antibody (OTI5C8)
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Catalog No. PIMA527202
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100 μL
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PIMA527202 100 μL
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Catalog No. PIMA527202 Supplier Invitrogen™ Supplier No. MA527202
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Description

Mouse Monoclonal Antibody

TIMM8A Monoclonal Antibody for Western Blot, IHC (P)

Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TIMM8A
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone OTI5C8
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TIMM8A
Gene Accession No. O60220
Gene Alias DDP; Ddp1; deafness dystonia protein 1; Deafness dystonia protein 1 homolog; deafness/dystonia peptide; DFN1; DXHXS1274E; Fci-12; Mitochondrial import inner membrane translocase subunit Tim8 A; MTS; TIM8; Tim8a; Timm8a; Timm8a1; translocase of inner mitochondrial membrane 8 homolog a; translocase of inner mitochondrial membrane 8 homolog A (yeast); translocase of inner mitochondrial membrane 8 homolog a1; translocase of inner mitochondrial membrane 8 homolog A1 (yeast); translocase of inner mitochondrial membrane 8A1; X-linked deafness dystonia protein
Gene Symbols TIMM8A
Host Species Mouse
Immunogen Full length human recombinant protein of TIMM8A produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1678
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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