TIMM8A Mouse anti-Human, Clone: OTI5C8, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF809738

Catalog No. 50-166-9690

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predomit TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.

Specifications

• Antigen: TIMM8A
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TIMM8A
• Gene Alias: DDP, DDP1, DFN1, MTS, TIM8
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 1678
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI5C8
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: O60220
• Gene Symbols: TIMM8A
• Immunogen: Full length human recombit protein of human TIMM8A produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1