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TIMM8A Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501981653
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50-198-1653 100 μL
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Catalog No. 50-198-1653 Supplier Bioss Supplier No. BS11769R
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Description

Rabbit Polyclonal Antibody

Mitochondrial intermembrane chaperone that participates in the import and insertion of some multi-pass transmembrane proteins into the mitochondrial inner membrane. Also required for the transfer of beta-barrel precursors from the TOM complex to the sorting and assembly machinery (SAM complex) of the outer membrane. Acts as a chaperone-like protein that protects the hydrophobic precursors from aggregation and guide them through the mitochondrial intermembrane space. The TIMM8-TIMM13 complex mediates the import of proteins such as TIMM23, SLC25A12/ARALAR1 and SLC25A13/ARALAR2, while the predominant TIMM9-TIMM10 70 kDa complex mediates the import of much more proteins. Probably necessary for normal neurologic development.

Specifications

Antigen TIMM8A
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene TIMM8A
Gene Accession No. O60220
Gene Alias DDP; DDP1; Deafness dystonia protein 1; Deafness dystonia protein 1 homolog; deafness/dystonia peptide; DFN1; DXHXS1274E; Fci-12; Mitochondrial import inner membrane translocase subunit Tim8 A; MTS; TIM8; TIM8A; TIMM8A; Timm8a1; translocase of inner mitochondrial membrane 8 homolog a; translocase of inner mitochondrial membrane 8 homolog A (yeast); translocase of inner mitochondrial membrane 8 homolog a1; translocase of inner mitochondrial membrane 8 homolog A1 (yeast); translocase of inner mitochondrial membrane 8A1; X-linked deafness dystonia protein
Gene Symbols TIMM8A
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TIMM8A.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1678
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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