TIMP-2 Antibody (3A4), DyLight 594, Novus Biologicals™

Mouse Monoclonal Antibody

Supplier:  Novus Biologicals NBP254555DL594

Catalog No. NB008358

Description

TIMP-2 Monoclonal specifically detects TIMP-2 in Human, Mouse, Rat, Bovine, Guinea Pig, Rabbit, Zebrafish samples. It is validated for Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin.

Specifications

• Antigen: TIMP-2
• Classification: Monoclonal
• Conjugate: DyLight 594
• Formulation: 50mM Sodium Borate with 0.05% Sodium Azide
• Gene Symbols: TIMP2
• Immunogen: A synthetic peptide from the N-terminus of human TIMP-2 protein (aa56-66) (DSGNDIYGNPI) (Uniprot: P16035)
• Quantity: 0.1 mL
• Research Discipline: Angiogenesis, Cancer, Cell Biology, Cell Cycle and Replication, Cellular Markers
• Test Specificity: It recognizes a protein of 21kDa, identified as tissue inhibitor of metalloproteinases-2 (TIMP-2). It is closely related to TIMP-1 and shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
• Content And Storage: Store at 4°C in the dark.

• Applications: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)
• Clone: 3A4
• Dilution: Western Blot, Flow Cytometry, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunohistochemistry-Paraffin
• Gene Alias: CSC-21Ktissue inhibitor of metalloproteinase 2, metalloproteinase inhibitor 2, TIMP metallopeptidase inhibitor 2, TIMP-2, Tissue inhibitor of metalloproteinases 2
• Host Species: Mouse
• Purification Method: Protein A or G purified
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat, Bovine, Guinea Pig, Rabbit, Zebrafish
• Isotype: IgG2a κ