TIMP-4 Rabbit anti-Human, Polyclonal, Proteintech

Catalog No.	Quantity
50-172-7895	150 μL

Catalog No. 50-172-7895 Supplier Proteintech Group Inc Supplier No. 123261AP150UL

Description

Rabbit Polyclonal Antibody

Tissue inhibitor of metalloproteinase 4 (TIMP4) is encoded by the gene TIMP4 located on chromosome 3. It belongs to the family of TIMP genes and is known to inhibit the activity of matrix metalloproteinases. Matrix metalloproteinases (MMP) are a group of proteinases that degrade the components of extracellular matrix. TIMP4 irreversibly binds to MMPs and inactivates them with the help of zinc as a cofactor. The netrin domain of TIMP4 is involved in platelet recruitment and aggregation. Other biological functions include response to cytokine and peptide hormone stimuli and involvement with the ovulation cycle and CNS development.

Specifications

• Antigen: TIMP-4
• Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 0.27 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
• Gene: TIMP4
• Gene Accession No.: Q99727
• Gene Alias: Metalloproteinase inhibitor 4, TIMP 4, TIMP4, TIMP-4
• Gene Symbols: TIMP4
• Host Species: Rabbit
• Immunogen: TIMP-4 Fusion Protein Ag2927
• Purification Method: Antigen Affinity Chromatography
• Quantity: 150 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7079
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG