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TIMP2 Monoclonal Antibody (T2-101), Invitrogen™

Catalog No. PIMA513603
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500 μL
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PIMA513603 500 μL
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Catalog No. PIMA513603 Supplier Thermo Scientific Supplier No. MA513603
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Description

Mouse Monoclonal Antibody

MA5-13603 targets TIMP-2 in Immunoprecipitation and Western blot applications and shows reactivity with Human samples. The MA5-13603 immunogen is native human pro-MMP-2/TIMP-2 complex purified from A2058 culture medium followed by purified human rTIMP-2.

TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TIMP2
Applications Immunoprecipitation, Western Blot
Classification Monoclonal
Clone T2-101
Concentration 0.2 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.2% BSA and 0.09% sodium azide; pH 7.4
Gene TIMP2
Gene Accession No. P16035, P25785
Gene Alias Collagenase inhibitor; CSC-21K; D11Bwg1104e; DDC8; etID32613.12; fa96h09; Metalloproteinase inhibitor 2; metalloproteinase inhibitor 2a; metalloproteinase inhibitor precursor; metalloproteinase inhibitor TIMP-2; metalloproteinase-2; similar to metalloproteinase inhibitor; testicular secretory protein Li 57; TIMP 2; TIMP metallopeptidase inhibitor 2; TIMP metallopeptidase inhibitor 2a; TIMP2; Timp-2; TIMP-2 protein; timp2a; tissue inhibitor of matrix metalloproteinase-2; tissue inhibitor of metalloproteinase 2; tissue inhibitor of metalloproteinase 2 precursor; tissue inhibitor of metalloproteinase 2a; tissue inhibitor of metalloproteinase-2; tissue inhibitor of metalloproteinase-2 precursor; tissue inhibitor of metalloproteinases 2; tissue inhibitor of mettaloproteinase 2; wu:fa96h09; zgc:136726
Gene Symbols TIMP2
Host Species Mouse
Immunogen Native human pro-MMP-2/TIMP-2 complex purified from A2058 culture medium followed by purified human rTIMP-2
Purification Method Protein G
Quantity 500 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21858, 7077
Target Species Human, Mouse
Content And Storage 4° C
Product Type Antibody
Form Liquid
Isotype IgG1
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