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TIMP2 Mouse anti-Human, Clone: 4C7, Bioss
SDP

Catalog No. 501979846
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100 μL
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50-197-9846 100 μL
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Catalog No. 50-197-9846 Supplier Bioss Supplier No. BSM51320M
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Description

Mouse Monoclonal Antibody

TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintenance of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72 kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92 kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Specifications

Antigen TIMP2
Applications Flow Cytometry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 4C7
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation TBS with 1% BSA, 40% glycerol and 0.05% sodium azide; pH
Gene TIMP2
Gene Accession No. P16035
Gene Alias BOS_19535; Collagenase inhibitor; CSC-21K; D11Bwg1104e; DDC8; Metalloproteinase inhibitor 2; metalloproteinase inhibitor TIMP-2; testicular secretory protein Li 57; TIMP metallopeptidase inhibitor 2; Timp2; Timp-2; tissue inhibitor of matrix metalloproteinase-2; tissue inhibitor of metalloproteinase 2; tissue inhibitor of metalloproteinase-2; Tissue inhibitor of metalloproteinases 2; tissue inhibitor of mettaloproteinase 2
Gene Symbols TIMP2
Host Species Mouse
Immunogen This TIMP2 antibody is generated from a mouse immunized with arecombinant protein of human TIMP2.
Purification Method Protein G
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7077
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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