TIMP2 Mouse anti-Human, Clone: F27P3A4, Abnova™

Catalog No.	Quantity
89-935-012	50 μg

Catalog No. 89-935-012 Supplier Abnova Corporation Supplier No. MAB12521

Description

Mouse monoclonal antibody raised against human TIMP2.

This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix. [provided by RefSeq]

Specifications

• Antigen: TIMP2
• Applications: ELISA, Immunohistochemistry (PFA fixed), Western Blot
• Classification: Monoclonal
• Clone: F27P3A4
• Conjugate: Unconjugated
• Description: Mouse monoclonal antibody raised against human TIMP2.
• Dilution: ELISA Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (10 ug/mL) Western Blot The optimal working dilution should be determined by the end user.
• Formulation: In PBS, pH 7.2 (0.09% sodium azide).
• Gene Alias: CSC-21K
• Gene Symbols: TIMP2
• Host Species: Mouse
• Immunogen: A synthetic peptide corresponding to human TIMP2.
• Purification Method: Affinity purification
• Quantity: 50 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 7077
• Target Species: Human
• Content And Storage: Store at 4°C. For long term storage store at -20°C.
  Aliquot to avoid repeated freezing and thawing.
• Form: Liquid
• Isotype: IgG2a