TIMP2 Mouse anti-Human, Clone: OTI2G7, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF504018

Catalog No. 50-166-2572

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

TIMP-1 and TIMP-2 are inhibitory enzymes of matrix metalloproteinase family, and are thought to be of great importance in the maintece of connective tissue integrity. TIMP-2 shows the highest binding affinity to both the latent (pro) and active forms of 72kDa Type IV collagenase (also known as MMP-2 or gelatinase A). It also has affinity for the active form of 92kDa Type IV collagenase (also known as MMP-9 or gelatinase B). TIMP-2 inhibits the proteolytic invasiveness of tumor cells and normal placental trophoblast cells.

Specifications

• Antigen: TIMP2
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TIMP2
• Gene Alias: CSC-21K, DDC8
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 7077
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Flow Cytometry, Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI2G7
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: P16035
• Gene Symbols: TIMP2
• Immunogen: Full length human recombit protein of human TIMP2 produced inHEK293T cell.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG1