Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More

Invitrogen™ TIMP3 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578423

Catalog No. PIPA578423


Only null left
Add to Cart

Description

Description

Positive Control: mouse kidney Predicted Reactivity: Human (100%), Rat (97%), Xenopus laevis (83%), Dog (100%), Rabbit (97%), Chicken (82%), Sheep (100%), Rhesus Monkey (100%), Bovine (97%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Tissue inhibitor of metalloproteinase 3 (TIMP3) is a member of the tissue inhibitor of metalloproteinases gene family. It functions to inhibit the activity of matrix metalloproteinases (MMP) which degrade components of the extracellular matrix. TIMP3 is expressed upon mitogenic stimulation. It binds irreversibly to zinc-dependent MMPs and inactivates them by binding to their catalytic zinc cofactor. Other functions of TIMP3 include nervous system development, tissue regeneration, and visual perception. In humans, the gene encoding TIMP3 is located on chromosome 22.
TRUSTED_SUSTAINABILITY
Specifications

Specifications

TIMP3
Polyclonal
Unconjugated
TIMP3
HSMRK222; K222; K222TA2; Metalloproteinase inhibitor 3; MIG-5 protein; protein MIG-5; SFD; Sun; TIMP 3; TIMP metallopeptidase inhibitor 3; TIMP metallopeptidase inhibitor 3 (Sorsby fundus dystrophy, pseudoinflammatory); TIMP metallopeptidase inhibitor 3 L homeolog; timp3; TIMP-3; TIMP-3 protein; timp3.L; timp3-A; tissue inhibitor metalloproteinase-3; tissue inhibitor of metalloproteinase 3; tissue inhibitor of metalloproteinase 3 (Sorsby fundus dystrophy, pseudoinflammatory); tissue inhibitor of metalloproteinase-3; tissue inhibitor of metalloproteinase-3 precursor; tissue inhibitor of metalloproteinases 3; tissue inhibitor of metalloproteinases-3; XELAEV_18002484mg
Rabbit
Antigen affinity chromatography
RUO
21859, 25358, 7078
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Liquid
Western Blot, Immunocytochemistry
0.51 mg/mL
0.1M tris glycine with 10% glycerol, 0.1M glycine and 0.01% thimerosal; pH 7
P35625, P39876, P48032
TIMP3
Recombinant protein encompassing a sequence within the center region of human TIMP3. The exact sequence is proprietary.
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
Product Suggestions

Product Suggestions

Videos
Safety and Handling

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
SDS
Documents

Documents

Product Certifications
Promotions

Promotions

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Your feedback has been submitted: Thank you for helping us improve our website.