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Invitrogen™ TIMP4 Polyclonal Antibody
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Catalog No. PIPA523657
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400 μL
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Catalog No. Quantity
PIPA523657 400 μL
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Catalog No. PIPA523657 Supplier Invitrogen™ Supplier No. PA523657
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Description

Rabbit Polyclonal Antibody

TIMP4 Polyclonal Antibody for Western Blot, IHC (P)

Tissue inhibitor of metalloproteinase 4 (TIMP4) is encoded by the gene TIMP4 located on chromosome 3. It belongs to the family of TIMP genes and is known to inhibit the activity of matrix metalloproteinases. Matrix metalloproteinases (MMP) are a group of proteinases that degrade the components of extracellular matrix. TIMP4 irreversibly binds to MMPs and inactivates them with the help of zinc as a cofactor. The netrin domain of TIMP4 is involved in platelet recruitment and aggregation. Other biological functions include response to cytokine and peptide hormone stimuli and involvement with the ovulation cycle and CNS development.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TIMP4
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Conjugate Unconjugated
Formulation PBS with 0.09% sodium azide; pH 7.4
Gene TIMP4
Gene Accession No. Q99727, Q9JHB3
Gene Alias Metalloproteinase inhibitor 4; TIMP 4; TIMP metallopeptidase inhibitor 4; TIMP4; TIMP-4; tissue inhibitor of metalloproteinase 4; tissue inhibitor of metalloproteinases 4
Gene Symbols TIMP4
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide between 48-74 amino acids from the central region of human TIMP4.
Purification Method Antigen affinity chromatography, Protein A
Quantity 400 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 110595, 7079
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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