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  5. Tocris Bioscience™ Tipifarnib

Tocris Bioscience™ Tipifarnib

Catalog No. 64105RD
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25 mg
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Catalog No. Quantity
64-105-RD 5 mg
64-102-5RD 25 mg
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Catalog No. 64-105-RD Supplier Tocris Bioscience™ Supplier No. 6410/5
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Description

Potent farnesyltransferase inhibitor; orally bioavailable

Tipifarnib is a potent farnesyltransferase inhibitor. Inhibits farnesylation of lamin B and K-RasB peptide substrates (IC50 values are 0.86 and 7.9 nM, respectively). Inhibits tumor growth in vitro and in vivo. Cell penetrant and orally bioavailable.

Specifications

Chemical Name or Material 6-[(R)-Amino(4-chlorophenyl)(1-methyl-1H-imidazol-5-yl)methyl}-4-(3-chlorophenyl)-1-methyl-2(1H)-quinolinone
CAS 192185-72-1
Quantity 5 mg
Molecular Formula C27H22Cl2N4O
Formula Weight 489.4
Purity 98%
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