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Invitrogen™ TIS11D Polyclonal Antibody
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Catalog No. PIPA536248
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PIPA536248 100 μL
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Catalog No. PIPA536248 Supplier Invitrogen™ Supplier No. PA536248
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Rabbit Polyclonal Antibody

This antibody detects endogenous protein at a molecular weight of 40 kDa. Purity is >95% by SDS-PAGE.

TIS11D, also known as ZFP36LA (zinc finger protein 36, C3H type-like 2), BRF2 (butyrate response factor 2), ERF2 or RNF162C, is a 494 amino acid protein that localizes to the nucleus and contains two CSH1-type zinc fingers. Belonging to the TIS11 family of early response proteins, TIS11D is thought to function as a nuclear transcription factor that binds to 5'UUAUUUAUUU-3' core RNA sequences and may regulate growth factor-induced cellular responses. The gene encoding TIS11D maps to human chromosome 2, which houses over 1, 400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TIS11D
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene ZFP36L2
Gene Accession No. P23949, P47974
Gene Alias Brf2; Butyrate response factor 2; EGF-response factor 2; ERF2; ERF-2; LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36L2; mRNA decay activator protein ZFP36L2; Protein TIS11D; RNF162C; TIS11D; TISD; TPA-induced sequence 11d; ZFP36 ring finger protein like 2; ZFP36 ring finger protein-like 2; ZFP36L2; ZFP36-like 2; zinc finger protein 36, C3H type-like 1; zinc finger protein 36, C3H type-like 2; zinc finger protein 36, C3H type-like 2-like; zinc finger protein 36, C3H1 type-like 2; zinc finger protein, C3H type, 36-like 2
Gene Symbols ZFP36L2
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acids 200-250 of human TIS11D.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12193, 298765, 678
Target Species Human, Mouse, Rat
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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WARNING: Cancer - www.P65Warnings.ca.gov
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