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Invitrogen™ TIS11D Polyclonal Antibody
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Catalog No. PIPA540708
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100 μL
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PIPA540708 100 μL
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Catalog No. PIPA540708 Supplier Invitrogen™ Supplier No. PA540708
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Description

Rabbit Polyclonal Antibody

Peptide sequence: VGTPVAAAPS SGFAPGFLRR HSASNLHALA HPAPSPGSCS PKFPGAANGS Sequence homology: Cow: 92%; Guinea Pig: 85%; Mouse: 84%; Rat: 84%.

TIS11D, also known as ZFP36LA (zinc finger protein 36, C3H type-like 2), BRF2 (butyrate response factor 2), ERF2 or RNF162C, is a 494 amino acid protein that localizes to the nucleus and contains two CSH1-type zinc fingers. Belonging to the TIS11 family of early response proteins, TIS11D is thought to function as a nuclear transcription factor that binds to 5'UUAUUUAUUU-3' core RNA sequences and may regulate growth factor-induced cellular responses. The gene encoding TIS11D maps to human chromosome 2, which houses over 1, 400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TIS11D
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene ZFP36L2
Gene Accession No. P47974
Gene Alias Brf2; Butyrate response factor 2; EGF-response factor 2; ERF2; ERF-2; LOW QUALITY PROTEIN: mRNA decay activator protein ZFP36L2; mRNA decay activator protein ZFP36L2; Protein TIS11D; RNF162C; TIS11D; TISD; TPA-induced sequence 11d; ZFP36 ring finger protein like 2; ZFP36 ring finger protein-like 2; ZFP36L2; ZFP36-like 2; zinc finger protein 36, C3H type-like 1; zinc finger protein 36, C3H type-like 2; zinc finger protein 36, C3H type-like 2-like; zinc finger protein 36, C3H1 type-like 2; zinc finger protein, C3H type, 36-like 2
Gene Symbols ZFP36L2
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human ZFP36L2 (aa 36-85).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 678
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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