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Invitrogen™ TK1 Recombinant Rabbit Monoclonal Antibody (JF0970)
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Catalog No. PIMA532513
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100 μL
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PIMA532513 100 μL
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Catalog No. PIMA532513 Supplier Invitrogen™ Supplier No. MA532513
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Rabbit Recombinant Monoclonal Antibody

Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.

Thymidine Kinase (TK1) is a highly conserved phosphotransferase that is present in most living cells. Thymidine Kinase catalyzes the phosphorylation reaction: deoxythymidine + ATP = deoxythymidine 5'-phosphate + ADP; it is thus involved in the reaction chain to introduce deoxythymidine into the DNA. Thymidine kinase is required for the action of many antiviral drugs, such as azidothymidine (AZT), and is also used to select hybridoma cell lines in the production of monoclonal antibodies. Thymidine Kinase has many clinical applications as it is only present in anticipation of cell division.
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Specifications

Antigen TK1
Applications Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry, Western Blot
Classification Recombinant Monoclonal
Clone JF0970
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation TBS with 0.05% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4
Gene TK1
Gene Accession No. P04183
Gene Alias D530002A18Rik; EC 2.7.1.21; KITH; thymidine kinase 1; thymidine kinase 1 soluble isoform; thymidine kinase 1, soluble; thymidine kinase, cytosolic; thymidine kinase-1; Tk; Tk1; Tk-1; Tk1a; Tk1b; TK2
Gene Symbols TK1
Host Species Rabbit
Immunogen Synthetic peptide within Human Thymidine Kinase 1 aa 2-49.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7083
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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