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Tocris Bioscience™ TL 12-186

Description
PROTAC comprised of a highly promiscuous kinase inhibitor conjugated to the cereblon E3 ubiquitin ligase ligand, pomalidomide (Cat. No. 6302). Degrades a range of kinases in MOLT-4 and MOLM-14 cell lines.
Negative control TL 13-27 (Cat. No. 6525) is also available.
Negative control TL 13-27 (Cat. No. 6525) is also available.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Specifications
Specifications
| Chemical Name or Material | N-(2-(2-(2-(4-(4-((5-Chloro-4-((2-(isopropylsulfonyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)piperazin-1-yl)ethoxy)ethoxy)ethyl)-2-((2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)amino)acetamide |
| CAS | 2250025-88-6 |
| Quantity | 5 mg |
| Molecular Formula | C44H51ClN10O9S |
| Formula Weight | 931.46 |
| Purity | 98% |
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