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Tocris Bioscience™ TL4-12

Potent MAP4K2 (GCK) inhibitor

Supplier:  Tocris Bioscience™ 5910/50

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Catalog No. 59-105-0


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Description

Description

TL4-12 is a potent MAP4K2 (GCK) inhibitor (IC50 = 37 nM). Exhibits >70-fold selectivity for MAP4K2 over TAK1 (IC50 = 2.7 μM for TAK1). Inhibits IL-1 and TGFβ-induced p38 MAPK phosphorylation, in vitro.
Specifications

Specifications

4-Methyl-3-[[6-(methylamino)-4-pyrimidinyl]oxy]-N-[3-(4-methyl-1-piperazinyl)-5-(trifluoromethyl)phenyl]benzamide
50 mg
98%
1620820-12-3
C25H27F3N6O2
Safety and Handling

Safety and Handling

Recommended Storage : Store at -20°C

SDS
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