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Invitrogen™ TLE1 Polyclonal Antibody
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Catalog No. PIPA596348
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PIPA596348 100 μL
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Catalog No. PIPA596348 Supplier Invitrogen™ Supplier No. PA596348
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Rabbit Polyclonal Antibody

Immunogen sequence: TGGKGCVKVW DISHPGNKSP VSQLDCLNRD NYIRSCKLLP DGCTLIVGGE ASTLSIWDLA APTPRIKAEL TSSAPACYAL AISPDSKVCF SCCSDGNIAV WDLHNQTLVR QFQGHTDGAS CIDISNDGTK LWTGGLDNTV RSWDLREGRQ LQQHDFTSQI FSLGYCPTGE WLAVGMESSN VEVLHVNKPD KYQLHLHESC VLSLKFAYCG KWFVSTGKDN LLNAWRTPYG ASIFQSKESS SVLSCDISVD DKYIVTGSGD KKATVYEVIY; Positive Samples: THP-1; Cellular Location: Nucleus.

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TLE1
Applications ELISA, Western Blot
Classification Polyclonal
Concentration 0.43 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene TLE1
Gene Accession No. Q04724
Gene Alias C230057C06Rik; E(Sp1) homolog; enhancer of split groucho; enhancer of split groucho-like protein 1; esg; ESG1; Estm14; grg1; Grg-1; Groucho-related protein 1; RP11-203D19.1; TLE 1; TLE1; tle1.S; tle3b; Tle4l; transducin like enhancer of split 1; transducin like enhancer of split 1 S homeolog; transducin-like enhancer of split 1 (E(sp1) homolog); transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 1, homolog of Drosophila E(spl); transducin-like enhancer of split 3 (E(sp1) homolog) b; transducin-like enhancer of split 4 (homolog of Drosophila E(spl)) - like; transducin-like enhancer protein 1; XELAEV_18001139mg; xgrg1
Gene Symbols TLE1
Host Species Rabbit
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 501-770 of human TLE1 (NP_0050682).
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 7088
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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