Invitrogen™ TLE1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA529086

Catalog No. PIPA529086

Description

Recommended positive controls: 293T. Predicted reactivity: Mouse (92%), Rat (92%), Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Specifications

• Antigen: TLE1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TLE1
• Gene Alias: C230057C06Rik; E(Sp1) homolog; enhancer of split groucho; enhancer of split groucho-like protein 1; esg; ESG1; Estm14; grg1; Grg-1; Groucho-related protein 1; RP11-203D19.1; TLE 1; TLE1; tle1.S; tle3b; Tle4l; transducin like enhancer of split 1; transducin like enhancer of split 1 S homeolog; transducin-like enhancer of split 1 (E(sp1) homolog); transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 1, homolog of Drosophila E(spl); transducin-like enhancer of split 3 (E(sp1) homolog) b; transducin-like enhancer of split 4 (homolog of Drosophila E(spl)) - like; transducin-like enhancer protein 1; XELAEV_18001139mg; xgrg1
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 362533, 7088
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Western Blot, Immunocytochemistry
• Concentration: 0.92 mg/mL
• Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
• Gene Accession No.: Q04724
• Gene Symbols: TLE1
• Immunogen: Recombinant protein encompassing a sequence within the center region of human TLE1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Rat
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov