Invitrogen™ TLE1 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA578200

Catalog No. PIPA578200

Description

Positive Control: 293T, HepG2 Predicted Reactivity: Rhesus Monkey (100%) Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

Transcriptional corepressor that binds to a number of transcription factors. Inhibits NF-kappa-B-regulated gene expression. Inhibits the transcriptional activation mediated by FOXA2, and by CTNNB1 and TCF family members in Wnt signaling. The effects of full-length TLE family members may be modulated by association with dominant-negative AES. Unusual function as coactivator for ESRRG.

Specifications

• Antigen: TLE1
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TLE1
• Gene Alias: C230057C06Rik; E(Sp1) homolog; enhancer of split groucho; enhancer of split groucho-like protein 1; esg; ESG1; Estm14; grg1; Grg-1; Groucho-related protein 1; RP11-203D19.1; TLE 1; TLE1; tle1.S; tle3b; Tle4l; transducin like enhancer of split 1; transducin like enhancer of split 1 S homeolog; transducin-like enhancer of split 1 (E(sp1) homolog); transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila); transducin-like enhancer of split 1, homolog of Drosophila E(spl); transducin-like enhancer of split 3 (E(sp1) homolog) b; transducin-like enhancer of split 4 (homolog of Drosophila E(spl)) - like; transducin-like enhancer protein 1; XELAEV_18001139mg; xgrg1
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 21885, 7088
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
• Concentration: 1.31 mg/mL
• Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
• Gene Accession No.: Q04724, Q62440
• Gene Symbols: TLE1
• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TLE1. The exact sequence is proprietary.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse
• Product Type: Antibody
• Isotype: IgG