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TLK2 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
SDP

Rabbit Polyclonal Antibody

Manufacturer:  Proteintech Group Inc 139791AP150UL

Encompass_Preferred

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Catalog No. 50-172-9136


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Description

Description

TLK2, a member of the Ser/Thr protein kinase family, is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. The TLK2 enzyme is cell-cycle regulated, with maximal activity in S-phase. It is inactivated by phosphorylation at Ser-750, potentially by CHK1. TLK2 heterodimerizes with TLK1. This nuclear protein is widely expressed, with presence in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle tissues, and in several adult cell lines.
Specifications

Specifications

TLK2
Polyclonal
Unconjugated
TLK2
PKU ALPHA, TLK2, tousled like kinase 2
Rabbit
Antigen Affinity Chromatography
RUO
11011, 24086, 303592
-20°C
Liquid
Immunocytochemistry, Immunofluorescence, Western Blot
0.17 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O55047, Q86UE8
TLK2
TLK2 Fusion Protein Ag5022
150 μL
Primary
Human, Mouse, Rat
Antibody
IgG
SDS
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