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TLK2 Rabbit anti-Human, Polyclonal, Bioss
SDP

Catalog No. 501988130
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50-198-8130 100 μL
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Catalog No. 50-198-8130 Supplier Bioss Supplier No. BS7925R
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Description

Rabbit Polyclonal Antibody

TLK2, a member of the Ser/Thr protein kinase family, is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. The TLK2 enzyme is cell-cycle regulated, with maximal activity in S-phase. It is inactivated by phosphorylation at Ser-750, potentially by CHK1. TLK2 heterodimerizes with TLK1. This nuclear protein is widely expressed, with presence in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle tissues, and in several adult cell lines.

Specifications

Antigen TLK2
Applications Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 μg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
Gene Tlk2
Gene Accession No. Q86UE8
Gene Alias 4933403M19Rik; HsHPK; PKUalpha; PKU-alpha; protein kinase U-alpha; Serine/threonine-protein kinase tousled-like 2; Tlk; Tlk2; tousled like kinase 2; Tousled-like kinase 2; tousled-like kinase 2 (Arabidopsis)
Gene Symbols Tlk2
Host Species Rabbit
Immunogen KLH conjugated synthetic peptide derived from human TLK2.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 11011
Target Species Human
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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