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  6. Invitrogen™ TLR4/MD-2 Complex Monoclonal Antibody (MTS510), Super Bright™ 436, eBioscience™, Invitrogen™ 

Invitrogen™ TLR4/MD-2 Complex Monoclonal Antibody (MTS510), Super Bright™ 436, eBioscience™, Invitrogen™
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Catalog No. 62992482
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100 μg
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Catalog No. Quantity
62-992-482 100 μg
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Catalog No. 62-992-482 Supplier Invitrogen™ Supplier No. 62992482
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Description

Rat Monoclonal Antibody

The MTS510 monoclonal antibody reacts with the mouse Toll-like receptor 4 (TLR4)/MD-2 complex. At least ten members of the Toll family have been identified. This family of type I transmembrane proteins is characterized by an extracellular domain with leuc

MD-2 is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs). TLRs are signaling molecules that recognize different pathogen-associated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses. TLR4, the major signaling receptor for lipopolysaccharide (LPS), requires the binding of MD-2 to its extracellular region for maximal response to LPS. The specificity of this response is determined by the species of MD-2; e.g., human MD-2 transfected into mouse cells can cause mouse TLR4 to react to LPS analogs that are normally antagonistic to human but not mouse TLR4.
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Specifications

Antigen TLR4/MD-2 Complex
Applications Flow Cytometry
Classification Monoclonal
Clone MTS510
Concentration 0.2 mg/mL
Conjugate Super Bright 436
Formulation PBS with BSA and 0.09% sodium azide; pH 7.2
Gene Ly96
Gene Accession No. Q9JHF9, Q9QUK6
Gene Alias ARMD10; CD284; Esop1; ESOP-1; hToll; lipopolysaccharide response; Lps; Ly87; Ly96; Ly-96; Lymphocyte antigen 96; Md2; MD-2; myeloid differentiation factor-2; myeloid differentiation protein-2; protein MD-2; Ran/M1; Rasl2-8; Tlr4; TLR-4; TOLL; Toll-like receptor 4
Gene Symbols Ly96, Tlr4
Host Species Rat
Purification Method Affinity chromatography
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 17087, 21898
Target Species Mouse
Content And Storage 4°C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG2a κ
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