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TLR8 Monoclonal Antibody (OTI2F5), TrueMAB™, OriGene
SDP

Catalog No. 501683248
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100 μL
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Catalog No. Quantity
50-168-3248 100 μL
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Catalog No. 50-168-3248 Supplier OriGene Supplier No. TA810191
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Description

Mouse Monoclonal Antibody

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). TLR8 gene contains three exons, two of which have coding function (4). TLR8 cDNA codes for a protein of approximate molecular weight of 120 kDa (4,5).

Specifications

Antigen TLR8
Applications Western Blot
Classification Monoclonal
Clone OTI2F5
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 1% BSA, 50% glycerol and 0.02% sodium azide
Gene TLR8
Gene Accession No. Q9NR97
Gene Alias CD288
Gene Symbols TLR8
Host Species Mouse
Immunogen Human recombit protein fragment corresponding to amino acids 32-153 of human TLR8 produced in E.coli.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51311
Target Species Human
Content And Storage -20° C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG1
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