TLR8 Mouse anti-Human, Clone: OTI4F3, lyophilized, TrueMAB™

Mouse Monoclonal Antibody

Supplier:  OriGene CF810174

Catalog No. 50-166-9930

Description

Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO

The Toll-like receptor (TLR) family in mammal comprises a family of transmembrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and IL-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylogenetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). TLR8 gene contains three exons, two of which have coding function (4). TLR8 cDNA codes for a protein of approximate molecular weight of 120 kDa (4,5).

Specifications

• Antigen: TLR8
• Classification: Monoclonal
• Conjugate: Unconjugated
• Gene: TLR8
• Gene Alias: CD288
• Host Species: Mouse
• Purification Method: Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51311
• Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
• Form: Lyophilized

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Clone: OTI4F3
• Formulation: PBS with 8% trehalose and no preservative; pH 7.3
• Gene Accession No.: Q9NR97
• Gene Symbols: TLR8
• Immunogen: Human recombit protein fragment corresponding to amino acids 32-153 of human TLR8 produced in E.coli.
• Quantity: 100 μg
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG2a