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Invitrogen™ TLR8 Polyclonal Antibody
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Catalog No. PIPA581956
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PIPA581956 100 μL
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Catalog No. PIPA581956 Supplier Invitrogen™ Supplier No. PA581956
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Rabbit Polyclonal Antibody

Immunogen sequence: RSYPCDEKKQ NDSVIAECSN RRLQEVPQTV GKYVTELDLS DNFITHITNE SFQGLQNLTK INLNHNPNVQ HQNGNPGIQS NGLNITDGAF LNLKNLRELL LEDNQLPQIP SGLPESLTEL SL Highest antigen sequence indentity to the following orthologs: Rat - 70%, Mouse - 70%.

The TLR8 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TLR8
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene TLR8
Gene Accession No. Q9NR97
Gene Alias CD antigen 288; CD288; TLR8; toll like receptor 8; toll-like receptor 8; UNQ249/PRO286
Gene Symbols TLR8
Host Species Rabbit
Immunogen Recombinant protein corresponding to Human TLR8. Recombinant protein control fragment (Product #RP-92131).
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 51311
Target Species Human
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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