Invitrogen™ TLR8 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA581956

Catalog No. PIPA581956

Description

Immunogen sequence: RSYPCDEKKQ NDSVIAECSN RRLQEVPQTV GKYVTELDLS DNFITHITNE SFQGLQNLTK INLNHNPNVQ HQNGNPGIQS NGLNITDGAF LNLKNLRELL LEDNQLPQIP SGLPESLTEL SL.

The TLR8 protein is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. The TLR8 gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X.

Specifications

• Antigen: TLR8
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TLR8
• Gene Alias: CD antigen 288; CD288; TLR8; toll like receptor 8; toll-like receptor 8; UNQ249/PRO286
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 51311
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.4 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q9NR97
• Gene Symbols: TLR8
• Immunogen: Recombinant protein corresponding to Human TLR8. Recombinant protein control fragment (Product #RP-92131).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

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