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Invitrogen™ TLR9 Polyclonal Antibody
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Catalog No. PIPA527258
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100 μL
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PIPA527258 100 μL
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Catalog No. PIPA527258 Supplier Invitrogen™ Supplier No. PA527258
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Rabbit Polyclonal Antibody

Recommended positive controls: THP-1, Recombinant TLR9 protein. Predicted reactivity: Rhesus Monkey (100%). Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The protein encoded by this gene is a member of the Toll-like receptor family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is preferentially expressed in immune cell rich tissues, such as spleen, lymph node, bone marrow and peripheral blood leukocytes. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TLR9
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 0.4 mg/mL
Conjugate Unconjugated
Formulation 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Tlr9
Gene Accession No. Q9EQU3, Q9NR96
Gene Alias CD289; Tlr9; toll like receptor 9; toll-like receptor 9; UNQ5798/PRO19605
Gene Symbols Tlr9
Host Species Rabbit
Immunogen Synthetic peptide encompassing a sequence within the Extracellular domain of human TLR9. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 54106, 81897
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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