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Invitrogen™ TLX Polyclonal Antibody
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Catalog No. PIPA5103055
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100 μL
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PIPA5103055 100 μL
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Catalog No. PIPA5103055 Supplier Invitrogen™ Supplier No. PA5103055
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total NR2E1.

Nuclear receptor TLX, a NR2 hepatocyte NF4-like receptor, has been shown to affect anterior brain differentiation, retinal development, and vision. It has been suggested that TLX targets genes for RAR beta2 and Pax2 during retinal development. Homozygous TLX mutant mice are viable at birth but exhibit reduced forebrain development and are more aggressive than wild-type mice. Mice with deleted TLX locus exhibit cerebral hypoplasia, blindness, and extreme aggression (fierce (frc) phenotype). TLX expression has been documented in mouse brain and eye. ESTs have been isolated from normal human brain libraries.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TLX
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene NR2E1
Gene Accession No. Q64104, Q9Y466
Gene Alias fc30e03; fc39f12; fierce; frc; HTll; Mtl1; Mtll; NR2D1; nr2e1; Nuclear receptor subfamily 2 group E member 1; nuclear receptor subfamily 2, group E, member 1; nuclear receptor TLX; Protein tailless homolog; tailes-related receptor; tailless; tailless homolog; TLL; Tlx; wu:fc30e03; wu:fc39f12; XTLL; zgc:100991
Gene Symbols NR2E1
Host Species Rabbit
Immunogen A synthesized peptide derived from human NR2E1(Accession Q9Y466), corresponding to amino acid residues G141-R191.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 21907, 684085, 7101
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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