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Invitrogen™ TLX1 Polyclonal Antibody
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Catalog No. PIPA546839
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100 μL
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PIPA546839 100 μL
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Catalog No. PIPA546839 Supplier Invitrogen™ Supplier No. PA546839
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Description

Rabbit Polyclonal Antibody

Peptide sequence: VAHPQPLATG LPTVPSVPAM PGVNNLTGLT FPWMESNRRY TKDRFTGHPY Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%.

The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX1, also called homeobox11 (HOX11), as it is located outside of the four mammalian Hox clusters, is a DNA-binding nuclear transcription factor. TLX1 encodes a homeobox-domain containing protein and is containing a glycine and proline-rich amino terminus. TLX1 is required for maintenance of the developing spleen and cell survival. TLX1 is highly expressed in T-cell leukemia and lymphoid neoplasias as a result of translocation. TLX1-deficient mice have no spleen.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TLX1
Applications Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene TLX1
Gene Accession No. P31314
Gene Alias homeo box-11 (T-cell leukemia-3 associated breakpoint, homologous to Drosophila Notch); homeobox protein Hox11; homeobox protein Hox-11; homeobox TLX-1; HOX11; Hox-11; LOW QUALITY PROTEIN: T-cell leukemia homeobox protein 1; MGC163402; proto-oncogene TCL-3; RGD1563655; SI:dZ46P4.1; T cell leukemia homeobox 1; T cell leukemia, homeobox 1; T-cell leukemia homeobox 1; T-cell leukemia homeobox protein 1; T-cell leukemia, homeobox 1; T-cell leukemia/lymphoma protein 3; TCL3; TLX1; Tlx-1; transcription factor; ztlx-1
Gene Symbols TLX1
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human TLX1.
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3195
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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