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Invitrogen™ TLX3 Polyclonal Antibody
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Catalog No. PIPA585574
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100 μL
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Catalog No. Quantity
PIPA585574 100 μL
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Catalog No. PIPA585574 Supplier Invitrogen™ Supplier No. PA585574
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Description

Rabbit Polyclonal Antibody

Keep as concentrated solution. Predicted reactivity: Mouse (100%), Xenopus laevis (100%), Chicken (100%), Bovine (100%). Positive Control: SK-N-SH, IMR32, SK-N-AS. Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.

The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX3, also known as homeobox11-like1 (HOX11L2), is a DNA-binding nuclear transcription factor that is expressed in a subset of the primary sensory nervous system. TLX3, along with the related TLX1, is a selector transcription factor that promotes an excitatory glutamatergic neuronal phenotype over an inhibitory GABAergic phenotype opposing LBX1 signals during dorsal spinal cord development. Chromosomal translocations of the TLX3 gene have been shown to result in some forms of T-cell acute lymphoblastic leukemia (T-ALL).
TRUSTED_SUSTAINABILITY

Specifications

Antigen TLX3
Applications Immunohistochemistry (Paraffin)
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 20% glycerol and 0.01% thimerosal; pH 7
Gene TLX3
Gene Accession No. O43711, O55144
Gene Alias homeo box 11-like 2; homeobox 11-like 2; homeobox protein Hox-11L2; Homeobox TLX-3; HOX11L2; Respiratory neuron homeobox protein; RGD1564190; RNX; T cell leukemia, homeobox 3; T-cell leukemia homeobox 3; T-cell leukemia homeobox protein 3; T-cell leukemia, homeobox 3; Tlx1l2; TLX3
Gene Symbols TLX3
Host Species Rabbit
Immunogen Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human TLX3. The exact sequence is proprietary.
Purification Method Antigen affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 27140, 30012
Target Species Human, Mouse
Content And Storage Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Type Antibody
Form Liquid
Isotype IgG
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