TLX3 Rabbit anti-Human, Polyclonal, Bioss

Catalog No.	Quantity
50-198-7147	100 μL

Catalog No. 50-198-7147 Supplier Bioss Supplier No. BS6240R

Description

Rabbit Polyclonal Antibody

The Hox proteins play a role in patterns of embryonic development and cellular differentiation by regulating downstream target genes. TLX3, also known as homeobox11-like1 (HOX11L2), is a DNA-binding nuclear transcription factor that is expressed in a subset of the primary sensory nervous system. TLX3, along with the related TLX1, is a selector transcription factor that promotes an excitatory glutamatergic neuronal phenotype over an inhibitory GABAergic phenotype opposing LBX1 signals during dorsal spinal cord development. Chromosomal translocations of the TLX3 gene have been shown to result in some forms of T-cell acute lymphoblastic leukemia (T-ALL).

Specifications

• Antigen: TLX3
• Applications: Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
• Classification: Polyclonal
• Concentration: 1 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 1% BSA, 50% glycerol and 0.09% sodium azide; pH
• Gene: TLX3
• Gene Accession No.: O43711
• Gene Alias: homeo box 11-like 2; homeobox 11-like 2; Homeobox protein Hox-11L2; Homeobox TLX-3; Hox11l2; Respiratory neuron homeobox protein; RGD1564190; Rnx; T cell leukemia, homeobox 3; T-cell leukemia homeobox 3; T-cell leukemia homeobox protein 3; T-cell leukemia, homeobox 3; Tlx1l2; Tlx3
• Gene Symbols: TLX3
• Host Species: Rabbit
• Immunogen: KLH conjugated synthetic peptide derived from human TLX3.
• Purification Method: Protein A
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 30012
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG