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Tocris Bioscience™ TM 5441
GREENER_CHOICE

Catalog No. 619410
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Quantity:
10 mg
50 mg
This item is not returnable. View return policy
This item is not returnable. View return policy

Description

Plasminogen activator inhibitor-1 (PAI-1) inhibitor

Plasminogen activator inhibitor-1 (PAI-1) inhibitor (IC50 = 3.58 - 60.3 μM). Increases apoptosis in human cancer cell lines. Reduces senescence and increases lifespan in mouse models of ageing (kl/kl). Inhibits L-NAME (Cat.No. 0665) induced systolic blood pressure increases, telomere length reduction and cardiac hypertrophy in mice. Renoprotective. Orally bioavailable.

Specifications

Quantity 10 mg
Solubility Soluble to 100mM in DMSO
Formula Weight 450.8
Physical Form Solid
Purity >98%
Chemical Name or Material 5-Chloro-2-[[2-[2-[[3-(3-furanyl)phenyl]amino]-2-oxoethoxy]acetyl]amino]benzoic acid sodium salt

Safety and Handling

Recommended Storage Store at +4°C
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