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Invitrogen™ TM4SF1 Recombinant Human Monoclonal Antibody (6B3)
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Catalog No. FEMA550228
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100 μL
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Catalog No. Quantity
FEMA550228 100 μL
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Catalog No. FEMA550228 Supplier Invitrogen™ Supplier No. MA550228
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Description

Human Recombinant Monoclonal Antibody

TM4SF1 Recombinant Monoclonal Antibody for Western Blot, Flow, ELISA

TM4SF1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains and mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. TM4SF1 is a cell surface antigen and is highly expressed in the vascular endothelium of several human cancers. Knockdown experiments of TM4SF1 prevented filopodia formation, inhibited cell mobility, blocked cytokinesis, and inhibited maturation of VEGF-A-induced angiogenesis, suggesting that TM4SF1 may be an attractive target for anti-angiogenesis therapy.
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Specifications

Antigen TM4SF1
Applications ELISA, Flow Cytometry, Western Blot
Classification Recombinant Monoclonal
Clone 6B3
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.03% Proclin 300; pH 7.4
Gene TM4SF1
Gene Accession No. P30408
Gene Alias 12A8 target antigen; H-L6; L6; L6 antigen; M3S1; Membrane component chromosome 3 surface marker 1; membrane component chromosome 3 surface marker 1 homolog; membrane component, chromosome 3, surface marker 1; membrane component, surface marker 1; TAAL6; TM4SF1; transmembrane 4 L six family member 1; transmembrane 4 L6 family member 1; transmembrane 4 superfamily member 1; tumor-associated antigen L6
Gene Symbols TM4SF1
Host Species Human
Immunogen Recombinant Human TM4SF1 protein.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 4071
Target Species Human
Content And Storage -20°C or -80°C if preferred
Product Type Antibody
Form Liquid
Isotype IgG1
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