Invitrogen™ TM4SF18 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA567048

Catalog No. PIPA567048

Description

Immunogen sequence: NGQTSYASSNK LTNYVWYFE Highest antigen sequence identity to the following orthologs - mouse 50%, rat 50%.

Transmembrane 4 L Six Family Member 18 (TM4SF18) is a gene located on chromosome 11q12.3 that belongs to the transmembrane 4 L six superfamily, a group of proteins characterized by the presence of four transmembrane domains. TM4SF18 is expressed in various tissues and is involved in cellular processes such as cell adhesion, migration, and proliferation. As part of the tetraspanin family, TM4SF18 proteins play a role in organizing cellular membranes and facilitating interactions between cell surface receptors, impacting signaling pathways crucial for maintaining cellular functions and tissue homeostasis. Although TM4SF18's specific biological roles are still being elucidated, it has been implicated in tumorigenesis, where altered expression may influence cancer progression by modulating cell-cell communication and migration. Research into TM4SF18 aims to uncover its precise functions in health and disease, particularly its potential involvement in cancer biology and as a target for therapeutic interventions.

Specifications

• Antigen: TM4SF18
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TM4SF18
• Gene Alias: AAB5; L6D; TM4SF18; transmembrane 4 L six family member 18; transmembrane 4 L6 family member 18
• Host Species: Rabbit
• Purification Method: Antigen Affinity Chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 116441
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin)
• Concentration: 0.05 mg/mL
• Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
• Gene Accession No.: Q96CE8
• Gene Symbols: TM4SF18
• Immunogen: Recombinant Human TM4SF18. Recombinant protein control fragment (Product #RP-107690).
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human
• Product Type: Antibody
• Isotype: IgG

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov