Invitrogen™ TM7SF3 Polyclonal Antibody

Catalog No.	Quantity
PIPA5144053	100 μg

Catalog No. PIPA5144053 Supplier Invitrogen™ Supplier No. PA5144053

Description

Rabbit Polyclonal Antibody

Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL. Positive Control - WB: human RT4 whole cell, human Jurkat whole cell, human MOLT-4 whole cell. Flow: SiHa cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

The TM7SF3 gene encodes transmembrane 7 superfamily member 3, a protein that is involved in cellular homeostasis and stress responses. TM7SF3 is characterized by its seven transmembrane domains, which contribute to its role in signal transduction across the cell membrane. This gene is expressed in various tissues and has been implicated in regulating cellular growth and survival pathways, proving critical in the context of cellular response to endoplasmic reticulum (ER) stress and maintaining cellular integrity. TM7SF3 modulates processes such as apoptosis and autophagy, particularly under stress conditions, thus influencing both normal physiological processes and pathological states like cancer. Research has shown that TM7SF3 expression can be altered in certain diseases, affecting pathways that govern cell cycle progression and stress adaptation. Understanding the role of TM7SF3 in cellular signaling and stress management can aid in identifying therapeutic targets for conditions characterized by dysfunctional cellular responses.

Specifications

• Antigen: TM7SF3
• Applications: ELISA, Flow Cytometry, Western Blot
• Classification: Polyclonal
• Concentration: 500 μg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 4mg trehalose and no preservative
• Gene: TM7SF3
• Gene Accession No.: Q9NS93
• Gene Alias: 2010003B14Rik; NARP1; Seven span transmembrane protein; seven transmembrane protein TM7SF3; TM7SF3; Transmembrane 7 superfamily member 3
• Gene Symbols: TM7SF3
• Host Species: Rabbit
• Immunogen: E.coli-derived human TM7SF3 recombinant protein (Position: R102-R544).
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μg
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 51768
• Target Species: Human
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Lyophilized
• Isotype: IgG