Invitrogen™ TMC7 Polyclonal Antibody

Catalog No.	Quantity
PIPA568352	100 μL

Catalog No. PIPA568352 Supplier Invitrogen™ Supplier No. PA568352

Description

Rabbit Polyclonal Antibody

Predicted to react with Mouse and Rat samples.

TMC7 (Transmembrane channel-like protein 7) is a 723 amino acid protein that is a member of the TMC protein family. All TMC genes encode transmembrane proteins with intracellular amino- and carboxy- termini and at least eight membrane spanning domains. Therefore, TMC7 is a multi-pass membrane protein that may regulate or function as an ion channel or transporter. The gene encoding TMC7 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Specifications

• Antigen: TMC7
• Applications: Western Blot
• Classification: Polyclonal
• Concentration: 1 mg/mL
• Conjugate: Unconjugated
• Formulation: PBS with 30% glycerol, 0.87% NaCl and 0.01% sodium azide; pH 7.4
• Gene: TMC7
• Gene Accession No.: Q7Z402, Q8C428
• Gene Alias: 1700030H01Rik; C230064B05; C630024K23Rik; RGD1564267; Tmc7; transmembrane channel like 7; transmembrane channel-like 7; transmembrane channel-like gene family 7; transmembrane channel-like protein 7
• Gene Symbols: TMC7
• Host Species: Rabbit
• Immunogen: Synthesized peptide derived from human TMC7.
• Purification Method: Antigen affinity chromatography
• Quantity: 100 μL
• Regulatory Status: RUO
• Primary or Secondary: Primary
• Gene ID (Entrez): 209760, 499254, 79905
• Target Species: Human, Mouse, Rat
• Content And Storage: -20°C
• Product Type: Antibody
• Form: Liquid
• Isotype: IgG