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Invitrogen™ TMC7 Polyclonal Antibody
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Catalog No. PIPA5104440
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100 μL
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PIPA5104440 100 μL
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Catalog No. PIPA5104440 Supplier Invitrogen™ Supplier No. PA5104440
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Description

Rabbit Polyclonal Antibody

Antibody detects endogenous levels of total TMC7.

TMC7 (Transmembrane channel-like protein 7) is a 723 amino acid protein that is a member of the TMC protein family. All TMC genes encode transmembrane proteins with intracellular amino- and carboxy- termini and at least eight membrane spanning domains. Therefore, TMC7 is a multi-pass membrane protein that may regulate or function as an ion channel or transporter. The gene encoding TMC7 maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMC7
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene TMC7
Gene Accession No. Q7Z402, Q8C428
Gene Alias 1700030H01Rik; C230064B05; C630024K23Rik; RGD1564267; Tmc7; transmembrane channel like 7; transmembrane channel-like 7; transmembrane channel-like gene family 7; transmembrane channel-like protein 7
Gene Symbols TMC7
Host Species Rabbit
Immunogen A synthesized peptide derived from human TMC7(Accession Q7Z402), corresponding to amino acid residues C676-N723.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 209760, 499254, 79905
Target Species Human, Mouse, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG
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Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
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