Invitrogen™ TMED5 Polyclonal Antibody

Rabbit Polyclonal Antibody

Supplier:  Invitrogen™ PA5141055

Catalog No. PIPA5141055

Description

TMED5 Polyclonal Antibody for Western Blot, IHC (P)

The TMED5 gene encodes transmembrane emp24 domain-containing protein 5, which is part of the p24 protein family involved in vesicular transport within the secretory pathway. TMED5 is predominantly localized in the endoplasmic reticulum and Golgi apparatus, where it plays a crucial role in the trafficking of secretory proteins. This protein is involved in the budding of transport vesicles and the selection of cargo molecules, assisting in their efficient transport through the secretory pathway. TMED5 is essential for maintaining cellular homeostasis and protein processing, impacting the secretion of various proteins that are vital for numerous physiological processes. Additionally, TMED5 has been implicated in pathological conditions related to protein misfolding and trafficking defects, highlighting its importance in cellular function and disease mechanisms. This gene's involvement in vesicular transport makes it a subject of interest, particularly in studies focusing on protein trafficking disorders and their therapeutic interventions.

Specifications

• Antigen: TMED5
• Classification: Polyclonal
• Conjugate: Unconjugated
• Gene: TMED5
• Gene Alias: CGI-100; p24 family protein gamma-2; p24g2; p24gamma2; p28; TMED5; Transmembrane emp24 domain-containing protein 5; transmembrane emp24 protein transport domain containing 5; transmembrane p24 trafficking protein 5; UNQ397/PRO733
• Host Species: Rabbit
• Purification Method: Antigen affinity chromatography
• Regulatory Status: RUO
• Gene ID (Entrez): 289883, 50999, 73130
• Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
• Form: Liquid

• Applications: Immunohistochemistry (Paraffin), Western Blot
• Concentration: 1 mg/mL
• Formulation: PBS with 0.1% BSA, 40% glycerol and 0.05% sodium azide; pH 7.4
• Gene Accession No.: Q6AXN3, Q9CXE7, Q9Y3A6
• Gene Symbols: TMED5
• Immunogen: Recombinant protein within Human TMED5 aa 1-200/229.
• Quantity: 100 μL
• Primary or Secondary: Primary
• Target Species: Human, Mouse, Rat
• Product Type: Antibody
• Isotype: IgG