Promotional price valid on web orders only. Your contract pricing may differ. Interested in signing up for a dedicated account number?
Learn More
  1. Home
  2. Products
  3. Antibodies
  4. Primary Antibodies
  5. All Primary Antibodies
  6. PIPA541292

Invitrogen™ TMEM108 Polyclonal Antibody
GREENER_CHOICE

Catalog No. PIPA541292
Change view
Click to view available options
Quantity:
100 μL
1 product options available for selection
Product selection table with 1 available options. Use arrow keys to navigate and Enter or Space to select.
Catalog No. Quantity
PIPA541292 100 μL
Use arrow keys to navigate between rows. Press Enter or Space to select a product option. 1 options available.
1 options
Catalog No. PIPA541292 Supplier Invitrogen™ Supplier No. PA541292
Add to Cart
Add to Cart

Description

Rabbit Polyclonal Antibody

Peptide sequence: NRLVPAGTWK PGTAGNISHV AEGDKPQHRA TICLSKMDIA WVILAISVPI Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%.

Transmembrane protein 108 (TMEM108) is a gene associated with psychiatric disorders such as schizophrenia, bipolar disorder, and major depression disorder. It is specifically expressed in the nervous system, particularly enriched in the postsynaptic density fraction and DG granule neurons. Research has shown that TMEM108 is critical for adult neurogenesis in the hippocampal dentate gyrus, indicating its role in neuronal development and function. Studies with TMEM108 mutant mice exhibit mania-like behavior, highlighting its involvement in the pathology of bipolar disorder. The gene's expression is notably higher in oligodendrocyte lineage cells within the central nervous system compared to other lineage cells. As a schizophrenia susceptibility gene, TMEM108 has been identified as a potential target for understanding the underlying mechanisms of psychiatric diseases and for developing therapeutic approaches. However, the detailed pathophysiological mechanisms by which TMEM108 contributes to such disorders remain largely unknown.
TRUSTED_SUSTAINABILITY

Specifications

Antigen TMEM108
Applications Western Blot
Classification Polyclonal
Concentration 1 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene TMEM108
Gene Accession No. Q6UXF1
Gene Alias AI462967; B130017P16Rik; cancer/testis antigen 124; CT124; KIAA1690; R74726; retrolinkin; RGD1311530; RTLN; TMEM108; Transmembrane protein 108; UNQ1875/PRO4318
Gene Symbols TMEM108
Host Species Rabbit
Immunogen Synthetic peptide directed towards the middle region of human TMEM108.
Purification Method Protein A
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 66000
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
Show More Show Less

Safety and Handling

WARNING: Cancer - www.P65Warnings.ca.gov
Product Title
Select an issue

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.